One of the things that I think was… was bad in… in Britain at the time was our very poor abilities in this kind of biochemistry. All the biochemistry was still very old fashioned, I mean, whereas in America the… the people emerging from the laboratories of Ochoa, from Kornberg... had by this time, you know, the huge armoury of materials. You see, Kornberg had a monopoly, well, you know, I don't want to put it like that, but really he had a monopoly of DNA replication because he was the only person who had radioactive triphosphates. And in fact in the Kornberg-Berg Lab, when a student came in, his first job was to make materials for the research, either prepare an enzyme… so the kind of strategic aspect… I mean, today you just phone up a company and buy it, but in those days getting into the technology and getting that tradition, working on protein synthesis, DNA replication, all of the messenger; there was hardly of this in Europe. And it was something that was very poor. And we realised, you know, coming as we did, that we would have to do some of this. So I think it was effectively, you know, the combination of not being able to get into that fast enough, and in fact we resolved thereafter that we would have… we would develop this biochemistry. I mean, Francis was always very keen to do this, but we didn't have the resources in the Cavendish. But when we moved to the new building we built up a lot of this biochemistry capability. But at the time, you know, we could do things, and in a way it was very good, because doing it by biochemistry just seemed awfully brute force. And since I think you had come... we had come to the position of being… prizing ingenuity beyond anything else, and elegance in the sense of being able just to sort of toss it away and do an experiment and say something profound from it – although I think that was more, you know, that was more a put on than reality, in other words a bit exaggerated – but I think that the lack of that kind of impetus, that kind of school of biochemistry, really held things back here.