I had been talking with Francis Crick about what we should do next and, you know, we felt we could now go and study the ribosome, for example. And you could set up a… a ribosomal project, and that would be we'd isolate all the proteins of the ribosome, we'd sequence all the proteins of the ribosome, and we'd then find out how ribosomes got built and how ribosomes got put together; we would do crystallography of the ribosomes and functional work. And indeed it took some 30 years for a few labs to do that program. Now we decided that none of these things seemed to us to be of great excitement, and one of the things that of course one had always been interested in – since I came from the study of animal cells, and Francis had a bit of a cell biology background himself – that of course we wanted to know something about higher organisms. And both of us were interested in the nervous system; I'd spent quite a lot of my youth working in it, but of course it was intractable at that stage. And so what I thought was: we now have all these powerful genetic tools; can't we use them to approach more complex problems?