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Do cells in culture lack an essential constituent?

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Cell replication is due to an internal cellular phenomenon
Leonard Hayflick Scientist
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We now had convinced ourselves of the authenticity of our finding that the failure of the cells finally to stop replicating must be due to some internal cellular phenomenon, and not to some external artefact like a virus or culture technique problems and any other external cell argument that you might propose for reasons that I describe, in particular, in a male-female experiment.

Leonard Hayflick (b. 1928), the recipient of several research prizes and awards, including the 1991 Sandoz Prize for Gerontological Research, is known for his research in cell biology, virus vaccine development, and mycoplasmology. He also has studied the ageing process for more than thirty years. Hayflick is known for discovering that human cells divide for a limited number of times in vitro (refuting the contention by Alexis Carrel that normal body cells are immortal), which is known as the Hayflick limit, as well as developing the first normal human diploid cell strains for studies on human ageing and for research use throughout the world. He also made the first oral polio vaccine produced in a continuously propogated cell strain - work which contributed to significant virus vaccine development.

Listeners: Christopher Sykes

Christopher Sykes is a London-based television producer and director who has made a number of documentary films for BBC TV, Channel 4 and PBS.

Tags: cell replication

Duration: 36 seconds

Date story recorded: July 2011

Date story went live: 08 August 2012