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The Hayflick limit
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Views | Duration | ||
---|---|---|---|
121. Frank Perkins | 56 | 02:37 | |
122. Human adult cell replication lower than fetal cell replication | 67 | 01:52 | |
123. Nathan Shock | 62 | 02:16 | |
124. Replacing WI-25 with WI-26 | 65 | 02:48 | |
125. Searching for healthy female fetal tissue | 181 | 04:29 | |
126. Laying down the first standards for vaccine production | 63 | 05:31 | |
127. The global distribution of WI-38 | 222 | 00:56 | |
128. The Hayflick limit | 2 | 220 | 02:06 |
129. Drago Ikić promotes the use of human cell culture | 72 | 02:11 | |
130. Worldwide production of vaccines using the WI-38 cell strain | 134 | 01:40 |
The subsequent events centred around all of the activities necessary to have the cells distributed for use. The WHO funded me to visit several countries in Europe and also to establish another bank of cells in Moscow for distribution among Iron Curtain countries, which was not easy to do, through Frank Perkins' WI-38 repository at MRC in London. Frank distributed cultures within the UK and within Western European countries, and also South America as well as Mexico, I should say.
Leonard Hayflick (b. 1928), the recipient of several research prizes and awards, including the 1991 Sandoz Prize for Gerontological Research, is known for his research in cell biology, virus vaccine development, and mycoplasmology. He also has studied the ageing process for more than thirty years. Hayflick is known for discovering that human cells divide for a limited number of times in vitro (refuting the contention by Alexis Carrel that normal body cells are immortal), which is known as the Hayflick limit, as well as developing the first normal human diploid cell strains for studies on human ageing and for research use throughout the world. He also made the first oral polio vaccine produced in a continuously propogated cell strain - work which contributed to significant virus vaccine development.
Title: The global distribution of WI-38
Listeners: Christopher Sykes
Christopher Sykes is a London-based television producer and director who has made a number of documentary films for BBC TV, Channel 4 and PBS.
Tags: World Health Organization, Frank Perkins
Duration: 56 seconds
Date story recorded: July 2011
Date story went live: 08 August 2012