We had another interesting experience at about that time, was this chap Steve Reeders who was going to find the gene for polycystic disease, and we had that... very few markers really, but by that time the alpha gene grew, done, got a lot more structural data on the alpha globin genes and I found these hypervariable regions and we had an excellent student at the time, Steve Goodbourn whose... whose PhD was to characterise these regions. I remember when he finished he came into my office one morning, great strip of paper, and said, 'There’s me thesis'. You know, I think he was getting a bit fed up by then. But he was on the next bench to the Reeders, and they were talking about this hypervariable region next to the alpha globin gene, so Steve had these Boston families with polycystic kidney disease, so he plugged them in, and there it was, it was very tight linkage. And at that stage it was difficult to keep good people, within I think a few weeks of that Nature paper, he’d been offered an Assistant Professorship at Yale, and the swine left. But fortunately, bloke who was helping him was not put off. In fact, we were told to stop working on it, by the MRC [Medical Research Council], but we went on, and as you know, they found this interesting patient from Cardiff, who had the nice deletion.

[Q] Originally from Portugal.

Originally from Portugal, that’s right. And so... so that was a really a bit of serendipity, and the nice thing of having people kind of working on different projects on the next bench.