Now of course there were lots of organisms that it would be interesting to know about, but which they were intractable or in some cases illegal to do genetic experiments. And of course that's why the genetics of man had gone so slowly, because we could only rely on certain markers and so on. But being able to approach that from the DNA just seemed to me to unify the whole of biology at one blow. And I think that when Wally Gilbert, or... it was Sinsheimer first suggested we should just sequence the whole  of the human genome, just like... genomes of whole organisms have been sequenced, but they were bacteriophages, they were 50,000 base pairs. And of course to jump from 50,000, from 10⁴, to three billion, that is 3 x 10⁹, that's a 10⁵ jump. That's, that was some act, I wouldn't call it of imagination, it's certainly a daring act. And of course a lot of people got together to say, yes, this is something that we would want to do.